As @Angina Seng has observed: $H_{n+1}-H_{n}=\frac{1}{n+1}$ and then your sum is $S=\sum_{n=0}^{\infty}{\binom{2n}{n}^{2}\over 16^{n}(n+1)^3}$ be the sum we want to evaluate.
If we consider the binomial expansions
\begin{equation}
2-2\sqrt{1-x}=\sum_{n=0}^{\infty}\binom{2n}{n}{x^{n+1}\over 4^{n}(n+1)}\tag{1},
\end{equation}
\begin{equation}
-4\log{2}+4\log{\left(1+\sqrt{1-x}\right)}-4\sqrt{1-x}+4=\sum_{n=0}^{\infty}{\binom{2n}{n}x^{n+1}\over 4^n(n+1)^2}\tag{2},
\end{equation}
where $(1)$ can be obtained from the binomial expansion of $(1-x)^{-1/2}$ after multiplying both sides by ${1 \over x}$, then integrating in $(0,x)$, and $(2)$ doing the same as with $(1)$.
The change $x=k^{2}\sin^{2}x$ in $(2)$ gives
\begin{equation}
4\log{\left({\sqrt{1-k^{2}\sin^{2}x}\over 2}+{1\over 2} \right)}-4\sqrt{1-k^{2}\sin^{2}x}+4=\sum_{n=0}^{\infty}{\binom{2n}{n}k^{2n+2}\sin^{2n+2}(x)\over 4^{n}(n+1)^{2}}\tag{3},
\end{equation}
The next step we do is integrate $(3)$ in $(0,{\pi\over 2})$ and apply Wallis formula to obtain
\begin{align}
2\pi\log\left({\sqrt{1-k^{2}}+1\over 4}\right)+4\int_{0}^{\pi \over 2}{x\cos{x}\over \sin{x}\sqrt{1-k^{2}\sin^{2}{x} }}dx-4E(k)+2\pi \\ \nonumber ={\pi\over 2}\sum_{n=0}^{\infty}{\binom{2n}{n}^{2}k^{2n+2}(n+1/2)\over 16^{n}(n+1)^{3}}\tag{4},
\end{align}
where $E(k)$ is the complete elliptic integral of the second kind.
Now we observe that
$$S=2S_{1}-S_{2},$$
where
$$S_{1}=\sum_{n=0}^{\infty}{\binom{2n}{n}^{2}\over 16^{n}(n+1)^{2}}\hspace{.5cm} and\hspace{.5cm} S_{2}=\sum_{n=0}^{\infty}{\binom{2n}{n}^{2}(2n+1)\over 16^{n}(n+1)^{3}}.$$
First we will see that $S_{1}={16\over \pi}-4$. See Calculate $\sum_{n = 0}^\infty \frac{C_n^2}{16^n}$ .
Finally setting $k=1$ in $(4)$
$$S_{2}=\sum_{n=0}^{\infty}{\binom{2n}{n}^{2}(2n+1)\over 16^{n}(n+1)^{3}}={4\over \pi}\left(-4\pi\log{2}+4\int_{0}^{\pi\over 2}{x\over \sin{x}}dx+2\pi-4\right) \\=-16\log{2}+{32G\over \pi}-{16\over \pi}+8,$$
where we have used the well known integral $\int_{0}^{\pi\over 2}{x\over \sin{x}}dx=2G$, being $G$ Catalan's constant. Then the desired sum is
\begin{align*}
S=2S_{1}-S_{2}=16\log{2}-{32G\over \pi}+{48\over \pi}-16.
\end{align*}